منابع مشابه
Behavior of Prions in the Environment: Implications for Prion Biology
Prion diseases are infectious, potentially zoonotic neurodegenerative diseases of animals including humans that are inevitably fatal and are caused by prions. Prions are comprised of a misfolded isoform of the normal prion protein, PrP, into the infectious conformation, PrP [1]. Of the known prion diseases, chronic wasting disease (CWD) of deer, elk, and moose is emerging. CWD was first identif...
متن کاملPrions.
The discovery of infectious proteins, denoted prions, was unexpected. After much debate over the chemical basis of heredity, resolution of this issue began with the discovery that DNA, not protein, from pneumococcus was capable of genetically transforming bacteria (Avery et al. 1944). Four decades later, the discovery that a protein could mimic viral and bacterial pathogens with respect to the ...
متن کاملPrions.
Infectious proteins (prions) are usually self-templating filamentous protein polymers (amyloids). Yeast prions are genes composed of protein and, like the multiple alleles of DNA-based genes, can have an array of "variants," each a distinct self-propagating amyloid conformation. Like the lethal mammalian prions and amyloid diseases, yeast prions may be lethal, or only mildly detrimental, and sh...
متن کاملPrions
plants are cloaked in hundreds of tiny projections, known as trichomes. These structures vary in function, shape, size and spacing from species to species, and it’s not known whether similar cellular differentiation programs are responsible for making trichomes in different plants. Trichomes are clearly visible in the scanning electron micrograph of a wild-type Nicotiana tabacum seedling above ...
متن کاملqfd planning with cost consideration in fuzzy environment
در عصر حاضر که رقابت بین سازمان ها بسیار گسترش یافته است، مطالعه و طرحریزی سیستم های تولیدی و خدماتی به منظور بهینه سازی عملکرد آنها اجتناب ناپذیر می باشد. بخش عمده ای از رقابت پذیری سازمان ها نتیجه رضایتمندی مشتریان آنها است. میزان موفقیت سازمان های امروزی به تلاش آنها در جهت شناسایی خواسته ها و نیازهای مشتریان و ارضای این نیازها بستگی دارد. از طرفی کوتاه کردن زمان ارائه محصول/خدمات به مشتریان...
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ژورنال
عنوان ژورنال: Prion
سال: 2008
ISSN: 1933-6896,1933-690X
DOI: 10.4161/pri.2.4.7951